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Immunohistochemistry (IHC) is a laboratory technique used to visualize the presence and distribution of specific proteins in tissue samples. The protocol involves fixing, embedding, and sectioning tissues, followed by incubation with primary antibodies targeting the protein of interest. Afterward, secondary antibodies conjugated with a detection system are applied, producing a visible signal. IHC is crucial in understanding the localization and expression levels of proteins within cells and tissues for diagnostic and research purposes.